We need your help to find treatments and a cure for MPAN.
MPAN is one of 10 known ultra-rare Neurodegeneration with Brain Iron Accumulation (NBIA) disorders.
With fewer than 300 people diagnosed worldwide, Mitochondrial-membrane Protein-Associated Neurodegeneration (MPAN) is caused by mutations in the C19orf12 gene found on chromosome 19. MPAN is one of the major forms of NBIA with distinctive symptoms such as spasticity that interferes with movement, speech, and walking, as well as vision loss and mental disorders.
Onset occurs in childhood to early adulthood. Most affected individuals are still able to walk as they reach adulthood. Psychiatric signs are common, including impulsive or compulsive behavior, depression and frequent mood changes. Unlike most other forms of NBIA, the vast majority of individuals with MPAN develop progressive cognitive decline.
Research funding is desperately needed to help find treatments and a cure.
Click on the Donate Now! button to make a gift for potentially life-saving research.
Help bring awareness to MPAN so we can fund potentially life-saving research. It’s easy. You can share about this on your social media. Or you can create a personal fundraising page of your own by clicking on the blue Raise Money for MPAN below . Share your story and say why this is important to you and your family. Add some photos too. Set your own fundraising goal, whether it is $40, $400 or $4,000. Choose any amount and just know: Every dollar makes a difference!
And don’t forget to promote your efforts or your page on Facebook and Twitter.
Don’t want to set up a page? How about hosting a picnic or another event to raise funds?
Only have time to send an email or two to family and friends? No problem. Tell them you need their help. Ask them to share your message with their friends and family or create their own page to raise awareness. Or they can donate directly by clicking MPAN.
HERE’S HOW YOU CAN HELP. We’re asking you to please consider joining with others to fund research for treatments and cures.
Please know that your contributions are tax-deductible to the full extent allowed by law because we are a charitable, 501(c)(3) organization.
Neurodegeneration with Brain Iron Accumulation is a group of rare, genetic neurological disorders characterized by abnormal accumulation of iron in the basal ganglia. The basal ganglia is a collection of structures deep within the base of the brain that assist in regulating movements.
In our drive to find a cure for NBIA, we provide support to families, educate the public and accelerate research with collaborators from around the world.